Now this is much needed if accurate. Science Daily reports that scientists at the University of Manchester, England have changed the surface coat of a class of antibiotics, providing a new array of drugs to battle the so-called superbugs that are highly resistant to standard drugs.
Scientists working in The School of Chemistry and the Manchester Interdisciplinary Biocentre have paved the way for the development of new types of antibiotics capable of fighting increasingly resistant bacteria.
Micklefield, Smith and colleagues were the first to engineer the biosynthesis of lipopeptide antibiotics of this class back in 2002. They have now developed methodologies for altering the structure of these antibiotics, such as mutating, adding and deleting components.
This innovation provides access to thousands of lipopeptide variants that cannot be produced easily in any other way.
Dr Micklefield said: “The results from this work are essential in the development of the next generation of lipopeptide antibiotics, which are critical to combat emerging super bugs that have acquired resistance to other antibiotics.
“The potent activity of this class of antibiotics against pathogens that are resistant to all current antibiotic treatments makes them one of the most important groups of antibiotics available.
“Our work relies on interdisciplinary chemical-biology, spanning chemistry through to molecular genetics. It follows the tradition of pioneering work in natural product biosynthesis and engineering that has come out of the UK.”
If accurate and workable, this could lead to new drugs against MRSA and many other drug resistant strains.
Greetings folks!
My name is Dean and I’m your humble blog moderator. I’ve always been fascinated in Science and Technology and it seems that for years now, areas of research have been gaining momentum at warp speed which is fascinating in itself. Though I’m not a scientist and don’t even play one on TV, I love the turns that science and technology are taking and want to share some of my more interesting findings of a SciTech nature with others.
I saw it put best years ago in, I dunno, some old magazine I ran across. “The augmentation of the intellect of man.” That’s what I’m after. I’d already been in the computer biz for quite a few years, but now watching nanotechnology taking shape and watching the discoveries of both outer and inner space that are taking place, I can’t for the life of me think of a better time to be alive.
Be warned however, that this is likely to be a hodgepodge of different subjects, astronomy, gadgets and gizmo’s, nanotechnology, chemistry, medicine, who knows. Whatever piques my interest is likely to end up here.
So sit back with a cup of java and let’s relax in each others company as we watch the human future unfold before us.
Dean